Mark Holthouse, M.D., FAAFP

Mark Holthouse, M.D., FAAFP

(Dr. Mark Holthouse MD, FAAFP, ABoIM, ABFM, ABIHM, IFMCP) 

After practicing Family Medicine from a traditional approach for over 20 years, I came to a point in my career where I wanted to look at medicine from a ROOT CAUSE perspective, not simply naming and blaming lists of symptoms patients came in with. I became frustrated with feeling like handing out prescription drugs and recommending surgery was all that I could do for people! None of the specialists were talking with each other and the patients never really got better…they just simply lived with more disease burden as time went along. In 2006 I started taking nutrition and integrative medicine course work and realized that I had finally found "my tribe". Shortly thereafter I started the Center for Functional & Integrative Medicine and later co-opened the True Health Center for Functional Medicine in El Dorado Hills, CA. 

During the past 10 years, I have obtained additional board certification by the American Board of Integrative & Holistic Medicine, the American Board of Integrative Medicine and become a Certified Functional Medicine Practitioner. I have opted to maintain my board in Family Medicine to keep both skill sets up to date. I now enjoy the broader perspective when my patient results come back showing improvements that I had been unable to obtain solely with the tools learned in medical school and residency. 

My favorite thing about being a physician is the opportunity to teach. I get to teach while practicing functional medicine here in the clinic and now in the academic arena as a professor at Loma Linda University School of Medicine. I am honored to teach the next generation of eager medical students in preventive cardiology and diabetes prevention. One of the highlights of my career has been my current opportunity to be part of the teaching faculty with The Institute for Functional Medicine, where I teach hormone health from a functional perspective to other physicians. Another great opportunity to educate my physician colleagues has been that of speaking on advanced cardiovascular risk assessment for the Cleveland Heart Lab Clinic. These and other technologies allow for earlier identification of patients at risk who would otherwise have been missed by traditional standard of care treatments.



Hours of Operation

Monday-Friday 8:30am - 5pm


  • Family Medicine Residency -University of California, Davis/David Grant Medical Center, Travis Air Force Base, CA
  • Loma Linda University School of Medicine- MD degree 
  • Pacific Union College - BS in Biology

Faculty Teaching Appointments:

  • Teaching Faculty at Institute for Functional Medicine 2014 to present
  • Assistant Professor of Medicine at Loma Linda University School of Medicine 2010 to present
  • U.C.  Davis School of Medicine Clinical Teaching Faculty  1993-1995
  • Chief of Ambulatory Care Mather and McClellan USAF Hospital/Clinics 1993-1996

Current Board Certifications

  • American Board of Family Medicine (ABFM)
  • American Board of Integrative Medicine (ABoIM) *Specialist
  • American Board of Integrative and Holistic Medicine (ABIHM)
  • Certified Functional Medicine Practitioner ( IFMCP)
  • Fellow American Academy of Family Practice (FAAFP)
  • Certified in The Bredesen Protocol by Dr. Dale Bredesen

Awards & Honors:

  • Best Family Physician in El Dorado County, El Dorado Hills  'Style Magazine Readers Choice Awards', consecutively from 2013 to 2017
  • Top Family Practitioner, Mountain Democrat Readers' Choice Awards 2007-2014
  • Major United States Air Force Medical Corp - USAF Commendation Medal Meritorious Service Award